Why we shall take NMN rather than NAD+?
NAD+ is a macromolecule, and it cannot be absorbed into bloodstream when delivered orally. At the same time, NAD+ is extremely unstable, and cannot be made into dietary supplement for long-term storage. Oral NMN can transform into NAD+ quickly in the body, which is the most direct and the fastest way to raise NAD+ level of the body so far.
Does alcohol affect the supplement?
Alcohol does not affect Origene® NMN dietary supplement, and it is recommended that you take it 2-3 hours before drinking alcohol.
Can tumor patients take it?
Tumor patients are not recommended to take NMN supplement; there are no related safety data of NMN dietary supplement’s effect on tumors. Under any circumstance of disease treatment, please consult your physician and follow the physician’s advice.
Is there any NMN dependence if one takes NMN?
Taking NMN only supplements insufficient NMN in human body effectively. Unlike common drugs for the treatment of disease, long-term use of NMN will not cause dependence. Also, it can be stopped instantly.
How does NMN improve energy and meliorate sleep?
NMN acts on human body by transforming into NAD+, which participates in various physiological metabolic reactions in the body, keeps them efficient and well-organized, instead of changing hormone or neurotransmitter for refreshing or sedation effects. At the same time, SUITUINS, activated by NAD+, can regulate circadian rhythm effectively, therefore, it can enhance energy and meliorate sleep.
What is a good NMN nutritional supplement?
Content：NMN nutritional supplement is a product that contains β-nicotinamide mononucleotide as single or major raw ingredient, in a measurable form such as tablet or capsule. The content of β-nicotinamide mononucleotide in the product should be not lower than 25mg/capsule (tablet). Commercially-available conventional content is 100-180mg, and more than 300mg can be achieved through top technology.
Purity：The higher the purity of the active ingredient , the more active ingredient there is; the higher the purity, the better. The highest purity in the market is as high as 99.9%.
Origin：Most products on the market are from Europe, America, Japan, and Hong Kong. Japan took the lead in clinical trials, and is the only country which lists NMN as both drug and food materials in the world. Therefore, Japanese authority has advanced and strict supervision for NMN raw material and production specification, safety, purity and analysis of the product.
Production
Chemical synthesis: simple process and cost effective; it is completed by compound reaction, and several organic solvents are involved as mediums. (Not recommended)
Fermentation: With the help of microorganism. The method is similar to wine-making. Low production efficiency and costly raw material go against industrial scale production. (Neutral)
Bio-enzyme catalysis: (holoenzyme and semi-enzyme) It is produced in a form of biosynthesis by specific engineered enzymes. NMN generated by this method has high purity; and the production mode is relatively moderate, and the whole process is slow and enduring. （Recommended)
Holoenzyme is the highest standard recognized and recommended in the NMN white paper.
Capsule：Most NMN products in the market adopt the form of capsules. Raw material for the capsule shells may have been derived from animals or plants. The cost of plant capsules is 3-5 times than that of ordinary gelatin capsules, and plant capsules can directly reach the intestinal tract, which makes NMN’s absorption rate higher.
Safety：For relatively new raw materials like NMN, it is not enough to judge their safety by manufacturers’ statement only, and it is particularly important to obtain the third party’s assessment report. There are two forms of general safety assessment reports. One is toxicology evaluation report and the other is safety assessment report.
